The Chicago Cubs (18-26) travel crosstown to play the Chicago White Sox (22-22) Saturday to start a 2-game interleague series at Guaranteed Rate Field. First pitch is set for 7:15 p.m. ET (FOX). Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. White Sox odds with MLB picks and predictions.
Both teams had Friday off. The Cubs are coming off a split of a 4-game series at the Cincinnati Reds early in the week. They are 4-6 in their last 10 games.
The White Sox lost the rubber match of their 3-game home set vs. the Boston Red Sox Thursday. Prior to that series, Chicago took 2 of 3 at the New York Yankees. The White Sox are 5-5 in their last 10.
Season series: White Sox lead 2-0
Cubs at White Sox projected starters
RHP Keegan Thompson vs. RHP Johnny Cueto
Thompson is 4-0 with a 1.54 ERA, 1.00 WHIP, 2.6 BB/9 and 8.0 K/9 in 35 IP over 2 starts and 8 relief appearances.
Last start: 7-0 home win vs. the Pittsburgh Pirates May 17 with 5-scoreless IP, 4 H, 0 BB and 5 K.
Pitched once since then, picking up a win after 3 innings of relief Sunday against the visiting Arizona Diamondbacks. He allowed 1 run on 2 hits with no walks, while striking out 4.
Cueto is 0-0 with a 0.00 ERA (12 IP, 0 ER), 8 H, 4 BB and 12 K in 2 starts.
Last start: No-decision in Chicago’s 3-1 win at the Yankees Sunday with 6-scoreless IP, 6 H, 2 BB and 5 K.
2021 vs. the Cubs: One start, a 4-3 loss with San Francisco Giants at Oracle Park. Surrendered 4 runs (3 earned) on 6 hits and 2 walks in 4 1/3 IP with 4 strikeouts.
Cubs at White Sox odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 4:02 p.m. ET.
Money line (ML): Cubs +122 (bet $100 to win $122) | White Sox -150 (bet $150 to win $100)
Run line (RL)/Against the spread (ATS): Cubs +1.5 (-170) | White Sox -1.5 (+135)
Over/Under (O/U): 7.5 (O: -130 | U: +105)
Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!
Cubs at White Sox picks and predictions
Cubs 5, White Sox 2
BET CUBS (+122).
There’s reverse-line movement (RLM) in their direction, the Cubs hit better against right-handed pitching and have a better bullpen than the White Sox.
More than 80% of the action is on the White Sox, per Pregame.com, but their ML has fallen from a -161 opener, which is suspicious, to say the least. This RLM is even more suspect considering the White Sox are 7-1 vs. the Cubs in their last 8 head-to-head meetings.
The Cubs have mediocre advanced-hitting numbers vs. right-handed pitching but the White Sox are dreadful. The White sox rank 26th in wRC+ (84), 27th in wOBA (.279), 26th in BB/K rate (0.29) and 29th in hard-hit rate (25.6%) against righties, according to FanGraphs.
Thompson serves as a “spot” starter, so the Cubs could get 5 or more innings of work from the bullpen, which is their strength. Cubs relievers are 1st in xFIP (3.22), per FanGraphs, and have much better swing-and-miss numbers and contact rates than the White Sox’s bullpen.
BET CUBS (+122).
Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! Use the couple code SBW22 for 20% OFF full-season subscription. New customer offer; expires 6/30/2022. Subscribe today and start winning!
Run line/Against the spread
Cubs +1.5 (-175) is out of my price range, but I wouldn’t rule out parlaying this with another similarly priced line for a better payout. The Cubs are 13-5 RL as road underdogs and the White Sox are just 8-14 RL at home.
LEAN to the UNDER 7.5 (+105).
There’s RLM headed south of the total, per Pregame.com, Thompson has been dealing this year, the Cubs have a good bullpen and the White Sox lineup has struggled vs. righties.
It’s only a LEAN because the Over is 7-3-1 O/U in their last 11 meetings and we have some money tied up in the Cubs’ ML.
Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!
If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.
Follow Geoff Clark on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.
Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup
Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).